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Fundamental principles of bhaishajya kalpana. The word Bhaishajya Kalpana is composed of two words – Bhaishajya and Kalpana. The word. Bhaishjya kalpana deals with the Basic Ayurvedic pharmaceutics. •The first systematic knowledge of Bhaishajya Kalpana is found in Caraka. Doctor of Medicine in Rasashastra & Bhaishajya Kalpana (Medicinal Chemistry and Pharmacy) is Non – Clinical course. Keeping with tradition, the course.

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Plant, animal or mineral jalpana in whatever nature they may be they can be hardly used as a drug in their natural form. In such a situation the therapeutically useful part of the substance needs to be separated out and put to therapeutic use. Hence almost bhishajya substance has to undergo a specific processing to acquire a form of palatable drug.

The boiling is continued till the liquid portion gets evaporated, at this stage the moisture of the fine paste vhaishajya evaporating. These are shown in Table 2. Dosage form Brief description Basti Per rectal administration of medicated oils and emulsions Guda varti Per rectal insertion of suppository Uttar Basti Per-urethral, per-vaginal administration of medicated oils and emulsions Nasya Nasal instillation and inhalations nasal insufflations Aschyotana Eye drops Anjana Eye creams and ointments Karnapurana Ear drops Ksaara a sutra Surgical thread coated with caustic or acrid drug material.

The powder should be fine at bhaisuajya of 80 mesh sieves. Varti, netrabindu and anjana – these are medicinal preparations meant for external application to the eyes. In a study carried out by SaxenaSilajatu a rock exudate samples obtained from five different places were evaluated for different types of pharmacological activities. Thesis submitted to Gujarat Ayurved University, Jamnagar.


Drug dosage forms having a longer stability are required by the patient and the health care provider. They are purified by boiling the raw material with different liquid materials till a soft mass is obtained and repeatedly processed to obtain its purified form known kalpama sodhita guggulu.


In one of the studies carried out in our lab Savrikar, three samples of guduchi ghritas were kallana using cow ghee ghrita obtained from three different regions- Wardha, Nanded and Solapur and the samples were evaluated for different pharmacological activities.

This is then made into thin sticks of about 2 centimeters in length and dried in shade. Where there are a number of drugs in yoga, the drugs are separately powdered and sieved. The stability period or shelf bhhaishajya of these dosage forms although in a generalized way has also been described by the classics.

Influence of season and place of collection In one of the studies it has been shown that season of collection of raw drugs can influence the expression of pharmacological activity Sridhara Bairy, Paarijaata Nyctanthes arbor-tristis Linn leaves collected in different seasons six samples were subjected to pharmacological bhaishaajya.

Bhaishajya Kalpanaa – The Ayurvedic Pharmaceutics – An Overview

In this respect edible substances are broadly divided in two categories: A combined solvent system is also used sometimes. This facilitates the extraction of the active principles contained in the drugs. It is possible that because of the ecological conditions prevailing in different parts from where the material is procured the same material collected from different regions may not have same activity profile.

Thesis submitted to Gujarat Ayurved University – Jamnagar. Ghana is a dried aqueous extract.

Shri Ayurved Mahavidyalaya

He further elaborates the concept by saying that not a single substance in the Universe is devoid of therapeutic potential and hence is bhaisajya potential drug source, provided it is used judiciously at appropriate indications. Apart from this the following plants should be used only till they retain their natural moisture: The components soluble in water are extracted in water whereas solvents like fat, oil or alcohol are required to extract ingredients soluble in those solvents.


Alternatively if the plant material is dry it is pulverized to yield fine powder. A critical review bhaishwjya Prakara yoga and Pharmaco-clinical study on a combination of certain drugs therein for Vyadhikshamatva effect and Brmhana in children. This indicates bhaishsjya preparation and processing oalpana can influence expression of pharmacological activity. Due to space constraint it is not possible to give full description of all these forms.

The five basic forms are: Depending on the requirement, different procedures are adopted to extract therapeutically useful ingredients. Many a times the substance may contain more than one therapeutically useful constituent.

Bhaishajya Kalpanaa – The Ayurvedic Pharmaceutics – An Overview

A detailed account of different stable dosage forms is given by the classics. Thus great bhaishajga and development efforts are required to optimize the formulation aspects to ensure constant availability of standardized products with constancy of composition and efficacy. The observed effect was compared against a water control group.

However, two of the varieties, namely Mahisa a ksha and Kanaka Guggulu are usually preferred for medicinal preparations. Influence of source of adjuvant or vehicle on the expression of pharmacological activity Many a times the place or source of materials especially of adjuvants and vehicles is not specified.

A study carried out by Rajesh Barvaliya on A-Panc a tikta ghrita literally translates as medicated ghee prepared from five drugs having bitter taste principles containing ghee involved preparation of the formulation by three methods and subjecting them to comparative study.

Considering its importance, different aspects of this discipline have been presented in this review to familiarize the readers, especially those who have just started studying Ayurveda, with concept of ayurvedic pharmaceutics. This shows that source of adjuvant itself may influence the expression of pharmacological activity.